Optomechanical proposal for monitoring microtubule mechanical vibrations

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985882%3A_____%2F17%3A00484820" target="_blank" >RIV/67985882:_____/17:00484820 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1103/PhysRevE.96.012404" target="_blank" >http://dx.doi.org/10.1103/PhysRevE.96.012404</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1103/PhysRevE.96.012404" target="_blank" >10.1103/PhysRevE.96.012404</a>

Result language

angličtina

Original language name

Optomechanical proposal for monitoring microtubule mechanical vibrations

Original language description

Microtubules provide the mechanical force required for chromosome separation during mitosis. However, little is known about the dynamic (high-frequency) mechanical properties of microtubules. Here, we theoretically propose to control the vibrations of a doubly clamped microtubule by tip electrodes and to detect its motion via the optomechanical coupling between the vibrational modes of the microtubule and an optical cavity. In the presence of a red-detuned strong pump laser, this coupling leads to optomechanical-induced transparency of an optical probe field, which can be detected with state-of-the art technology. The center frequency and line width of the transparency peak give the resonance frequency and damping rate of the microtubule, respectively, while the height of the peak reveals information about the microtubule-cavity field coupling. Our method opens the new possibilities to gain information about the physical properties of microtubules, which will enhance our capability to design physical cancer treatment protocols as alternatives to chemotherapeutic drugs

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10306 - Optics (including laser optics and quantum optics)

Project

<a href="/en/project/GA15-17102S" target="_blank" >GA15-17102S: Radio-frequency characterization of microtubules using micro- and nanosensors</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physical Review E

ISSN

2470-0045

e-ISSN

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Volume of the periodical

96

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

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UT code for WoS article

000405367200012

EID of the result in the Scopus database

2-s2.0-85026483051