Resolving controversy of unusually high refractive index of a tubulin

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985882%3A_____%2F17%3A00484852" target="_blank" >RIV/67985882:_____/17:00484852 - isvavai.cz</a>

Alternative codes found

RIV/68378050:_____/17:00484852

Result on the web

<a href="http://dx.doi.org/10.1209/0295-5075/117/38003" target="_blank" >http://dx.doi.org/10.1209/0295-5075/117/38003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1209/0295-5075/117/38003" target="_blank" >10.1209/0295-5075/117/38003</a>

Result language

angličtina

Original language name

Resolving controversy of unusually high refractive index of a tubulin

Original language description

The refractive index of a tubulin is an important parameter underlying fundamental electromagnetic and biophysical properties of microtubules - protein fibers essential for several cell functions including cell division. Yet, the only experimental data available in the current literature show values of the tubulin refractive index (n = 2.36-2.90) which are much higher than what the established theories predict based on the weighted contribution of the polarizability of individual amino acids constituting the protein. To resolve this controversy, we report here modeling and rigorous experimental analysis of the refractive index of a purified tubulin dimer. Our experimental data revealed that the refractive index of the tubulin is n = 1.64 at wavelength 589 nm and 25 degrees C, that is much closer to the values predicted by the established theories than what the earlier experimental data provide

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10306 - Optics (including laser optics and quantum optics)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Europhysics Letters

ISSN

0295-5075

e-ISSN

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Volume of the periodical

117

Issue of the periodical within the volume

3

Country of publishing house

FR - FRANCE

Number of pages

5

Pages from-to

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UT code for WoS article

000401165100001

EID of the result in the Scopus database

2-s2.0-85016803852