Synthesis of Stable Cerium Oxide Nanoparticles Coated with Phosphonic Acid-Based Functional Polymers
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985882%3A_____%2F23%3A00574760" target="_blank" >RIV/67985882:_____/23:00574760 - isvavai.cz</a>
Alternative codes found
RIV/62156489:43210/23:43923678 RIV/00216208:11320/23:10475818
Result on the web
<a href="https://doi.org/10.1021/acs.langmuir.3c00576" target="_blank" >https://doi.org/10.1021/acs.langmuir.3c00576</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acs.langmuir.3c00576" target="_blank" >10.1021/acs.langmuir.3c00576</a>
Alternative languages
Result language
angličtina
Original language name
Synthesis of Stable Cerium Oxide Nanoparticles Coated with Phosphonic Acid-Based Functional Polymers
Original language description
Functionalpolymers, such as poly(ethylene glycol) (PEG), terminatedwith a single phosphonic acid, hereafter PEG( ik)-Ph are often applied to coat metal oxide surfaces duringpost-synthesis steps but are not sufficient to stabilize sub-10 nmparticles in protein-rich biofluids. The instability is attributedto the weak binding affinity of post-grafted phosphonic acid groups,resulting in a gradual detachment of the polymers from the surface.Here, we assess these polymers as coating agents using an alternativeroute, namely, the one-step wet-chemical synthesis, where PEG( ik)-Ph is introduced with cerium precursorsduring the synthesis. Characterization of the coated cerium oxidenanoparticles (CNPs) indicates a core-shell structure, wherethe cores are 3 nm cerium oxide and the shell consists of functionalizedPEG polymers in a brush configuration. Results show that CNPs coatedwith PEG(1k)-Ph and PEG(2k)-Ph are of potentialinterest for applications as nanomedicines due to their high Ce(III)content and increased colloidal stability in cell culture media. Wefurther demonstrate that the CNPs in the presence of hydrogen peroxideshow an additional absorbance band in the UV-vis spectrum,which is attributed to Ce-O-2 (2-) peroxo-complexes and could be used in the evaluation of their catalyticactivity for scavenging reactive oxygen species.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10306 - Optics (including laser optics and quantum optics)
Result continuities
Project
<a href="/en/project/LM2015057" target="_blank" >LM2015057: Surface Physics Laboratory – Materials Science Beamline</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Langmuir
ISSN
0743-7463
e-ISSN
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Volume of the periodical
39
Issue of the periodical within the volume
23
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
8141-8152
UT code for WoS article
001011132500001
EID of the result in the Scopus database
2-s2.0-85162258621