Cerium oxide catalyzed disproportionation of hydrogen peroxide: a closer look at the reaction intermediate

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985882%3A_____%2F24%3A00584292" target="_blank" >RIV/67985882:_____/24:00584292 - isvavai.cz</a>

Alternative codes found

RIV/62156489:43210/24:43924498

Result on the web

<a href="https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202304012" target="_blank" >https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202304012</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/chem.202304012" target="_blank" >10.1002/chem.202304012</a>

Result language

angličtina

Original language name

Cerium oxide catalyzed disproportionation of hydrogen peroxide: a closer look at the reaction intermediate

Original language description

Cerium oxide nanoparticles (CNPs) have recently gained increasing interest as redox enzyme-mimetics to scavenge the intracellular excess of reactive oxygen species, including hydrogen peroxide (H2O2). Despite the extensive exploration, there remains a notable discrepancy regarding the interpretation of observed redshift of UV-Visible spectroscopy due to H2O2 addition and the catalase-mimicking mechanism of CNPs. To address this question, we investigated the reaction mechanism by taking a closer look at the reaction intermediate during the catalase mimicking reaction. In this study, we present evidence demonstrating that in aqueous solutions, H2O2 adsorption at CNP surface triggers the formation of stable intermediates known as cerium-peroxo (Ce-O22-) and/or cerium-hydroperoxo (Ce-OOH-) complexes as resolved by Raman scattering and UV-Visible spectroscopy. Polymer coating presents steric hinderance for H2O2 accessibility to the solid-liquid interface limiting further intermediate formation. We demonstrate in depth that the catalytic reactivity of CNPs in the H2O2 disproportionation reaction increases with the Ce(III)-fraction and decreases in the presence of polymer coatings. The developed approach using UV-Visible spectroscopy for the characterization of the surface peroxide species can potentially serve as a foundation for determining the catalytic reactivity of CNPs in the disproportionation of H2O2.nnThis study focuses on the reaction mechanism of H2O2 disproportionation by cerium oxide nanoparticles (CNP). In aqueous dispersions, H2O2 adsorption at CNP interfaces triggers the formation of stable intermediates known as cerium-peroxo complexes. The CNP catalytic reactivity is explored, showing an increase with Ce(III)-fraction and a decrease in the presence of polymer coatings, offering insights for potential nanomedicine applications.image

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10402 - Inorganic and nuclear chemistry

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chemistry - A European Journal

ISSN

0947-6539

e-ISSN

1521-3765

Volume of the periodical

30

Issue of the periodical within the volume

14

Country of publishing house

DE - GERMANY

Number of pages

11

Pages from-to

202304012

UT code for WoS article

001144435100001

EID of the result in the Scopus database

2-s2.0-85182647220