Structure and properties of porous films based on aliphatic copolyamide developed for cellular technologies

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985891%3A_____%2F15%3A00451058" target="_blank" >RIV/67985891:_____/15:00451058 - isvavai.cz</a>
Result on the web
<a href="http://www.stem-art.com/Library/Science/Structure%20and%20properties%20of%20porous%20films%20based%20on%20aliphatic%20copolyamide%20developed%20for%20cellular%20technologies.pdf" target="_blank" >http://www.stem-art.com/Library/Science/Structure%20and%20properties%20of%20porous%20films%20based%20on%20aliphatic%20copolyamide%20developed%20for%20cellular%20technologies.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10856-015-5381-y" target="_blank" >10.1007/s10856-015-5381-y</a>

Result language
angličtina
Original language name
Structure and properties of porous films based on aliphatic copolyamide developed for cellular technologies
Original language description
The effect of concentration and viscosity of the copolyamide (copolymer of epsilon-caprolactam and hexamethylendiaminadipate) solutions in aqueous/alcoholic solvents on its phase state was studied. The films obtained by the coagulation method were characterized by monodisperse pore distribution with an average pore size of 1.3 mu m. The films processed by electrospinning from copolyamide solutions were characterized by a bimodal distribution of macropores with one peak of pore radius at 2.0 mu m and second peak of pore radius at 20 mu m. The adhesion and proliferation of mesenchymal adhesion stem cells (ASCs) stem cells to copolyamide matrix were studied. With the help of scanning electron microscopy it was shown that both tapes porous films were characterized by good adhesion of mesenchymal ASCs stem cells. It was shown that the porous structure, transport and mechanical properties of these copolyamide films allow their use as two-dimensional matrices for cellular technology.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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