The Micro-CT Analysis of the Structural Parameters of Collagen-based Porous Scaffolds: The Influence of Image Processing and Binarization
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985891%3A_____%2F23%3A00566717" target="_blank" >RIV/67985891:_____/23:00566717 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11230/23:10453464 RIV/00216208:11110/23:10453464 RIV/00064165:_____/23:10453464
Result on the web
<a href="https://doi.org/10.1093/micmic/ozac024" target="_blank" >https://doi.org/10.1093/micmic/ozac024</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/micmic/ozac024" target="_blank" >10.1093/micmic/ozac024</a>
Alternative languages
Result language
angličtina
Original language name
The Micro-CT Analysis of the Structural Parameters of Collagen-based Porous Scaffolds: The Influence of Image Processing and Binarization
Original language description
The micro-CT evaluation of structural parameter values is dependent on the processing of the image prior to its analysis. However, the degree of bias introduced by the image-processing process is generally unknown. The micro-CT analysis of three basic parameters (volume, surface, and pore size) was performed for 20 collagen-based porous scaffolds. The image data were processed using various approaches (noise reduction, binarization), analyzed and results were compared. A high degree of variability was observed in the values of the structural parameters. The differences between the mean values were as follows: 190% (volume), 160% (surface density), and 210% (pore size). Significant differences were observed with respect to the noise reduction in terms of the pore size values (frequently in excess of 300%). Our study proved the significant dependence of image processing on the results obtained. The data presented can be used as an estimate for the introduced bias. We suggest improvements in terms of the selection of the image-processing approach based on a combination of subjective selection (the standard method) and numerical analysis based on the consistency of the results. Although we focused on tissue engineering scaffolds, the principles are similar for all fields of the micro-CT application.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30106 - Anatomy and morphology (plant science to be 1.6)
Result continuities
Project
<a href="/en/project/GA20-11186S" target="_blank" >GA20-11186S: Mechanics of arterial delamination and crack propagation</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Microscopy and Microanalysis
ISSN
1431-9276
e-ISSN
1435-8115
Volume of the periodical
29
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
244-253
UT code for WoS article
001033590800024
EID of the result in the Scopus database
2-s2.0-85153395811