The appearance of truncated cyclin A2 correlates with differentiation of mouse embryonic stem cells.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F03%3A19033058" target="_blank" >RIV/67985904:_____/03:19033058 - isvavai.cz</a>
Alternative codes found
RIV/67985904:_____/03:21033079 RIV/68378041:_____/03:21033079
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The appearance of truncated cyclin A2 correlates with differentiation of mouse embryonic stem cells.
Original language description
The presence of truncated form of cyclin A2 has been reported in various murine cell lines and tissues. In this paper it was shown that while undifferentiated proliferating mouse embryonic stem cells express low levels of this truncated cyclin A2, cellsthat are induced to differentiate remarkably increase its synthesis. Importantly, the expression pattern of truncated cyclin A2 was the same in p27 -/- ES cells as in the wild-type ES cells. Thus, it suggests that p27 is not necessary for the proteolyticcleavage of cyclin A2 and that this post-translational modification correlates with differentiation.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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