Tooth-bone morphogenesis during postnatal stages of mouse first molar development

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F11%3A00360057" target="_blank" >RIV/67985904:_____/11:00360057 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16170/11:43870592 RIV/61989592:15310/11:33119841
Result on the web
<a href="http://dx.doi.org/10.1111/j.1469-7580.2011.01367.x" target="_blank" >http://dx.doi.org/10.1111/j.1469-7580.2011.01367.x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1469-7580.2011.01367.x" target="_blank" >10.1111/j.1469-7580.2011.01367.x</a>

Result language
angličtina
Original language name
Tooth-bone morphogenesis during postnatal stages of mouse first molar development
Original language description
The first mouse molar (M1) is the most common model for odontogenesis, with research particularly focused on prenatal development. However, the functional dentition forms postnatally, when the histogenesis and morphogenesis of the tooth is completed, theroots form and the tooth physically anchors into the jaw. In this work, M1 was studied from birth to eruption, assessing morphogenesis, proliferation and apoptosis, and correlating these with remodeling of the surrounding bony tissue. The M1 completed crown formation between postnatal (P) days 0-2, and the development of the tooth root was initiated at P4. From P2 until P12, cell proliferation in the dental epithelium reduced and shifted downward to the apical region of the forming root. In contrast, proliferation was maintained or increased in the mesenchymal cells of the dental follicle. At later stages, before tooth eruption (P20), cell proliferation suddenly ceased.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EA - Morphology and cytology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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