Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors and overcoming their resistance
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F13%3A00442717" target="_blank" >RIV/67985904:_____/13:00442717 - isvavai.cz</a>
Result on the web
<a href="http://worldwide.espacenet.com/publicationDetails/biblio?CC=EP&NR=2602330" target="_blank" >http://worldwide.espacenet.com/publicationDetails/biblio?CC=EP&NR=2602330</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors and overcoming their resistance
Original language description
The present invention relates to a method for determining the sensitivity and/or resistance of a patient suffering from a cancer disease to Aurora kinase inhibitor therapy, which comprises determining in vitro in the cancer cells or body fluids taken from the patient the expression of at least one gene selected from a particular group and/or determining in vitro in the cancer cells or body fluids taken from the patient the level of at least one protein selected from a particular group. Also, the invention relates to a group of compounds which allow overcoming the resistance.
Czech name
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Czech description
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Classification
Type
P - Patent
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED2.1.00%2F03.0124" target="_blank" >ED2.1.00/03.0124: ExAM Experimental Animal Models</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Patent/design ID
EP2602330 (A1)
Publisher
EPO_1 -
Publisher name
European Patent Office
Place of publication
Munich, The Hague, Berlin, Vienna, Brussels
Publication country
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Date of acceptance
Jun 12, 2013
Owner name
Univerzita Palackého v Olomouci, Ústav živočišné fyziologie a genetiky AV ČR, v. v. i
Method of use
B - Výsledek je využíván orgány státní nebo veřejné správy
Usage type
A - K využití výsledku jiným subjektem je vždy nutné nabytí licence