Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors and overcoming their resistance
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F17%3A00531622" target="_blank" >RIV/67985904:_____/17:00531622 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/17:73586841
Result on the web
<a href="https://worldwide.espacenet.com/publicationDetails/biblio?CC=JP&NR=6144696B2&KC=B2&FT=D&ND=4&date=20170607&DB=&locale=en_EP#" target="_blank" >https://worldwide.espacenet.com/publicationDetails/biblio?CC=JP&NR=6144696B2&KC=B2&FT=D&ND=4&date=20170607&DB=&locale=en_EP#</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors and overcoming their resistance
Original language description
The present invention relates to a method for determining the sensitivity and/or resistance of a patient suffering from a cancer disease to Aurora kinase inhibitor therapy, which comprises determining in vitro in the cancer cells or body fluids taken from the patient the expression of at least one gene selected from a particular group and/or determining in vitro in the cancer cells or body fluids taken from the patient the level of at least one protein selected from a particular group. Also, the invention relates to a group of compounds which allow overcoming the resistance.
Czech name
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Czech description
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Classification
Type
P - Patent
CEP classification
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OECD FORD branch
10601 - Cell biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Patent/design ID
JP6144696
Publisher
JP001 -
Publisher name
Japan Patent Office (JPO)
Place of publication
Tokyo
Publication country
JP - JAPAN
Date of acceptance
Jun 7, 2017
Owner name
Palacky University Olomouc, Institute of Animal Physiology and Genetics, CAS
Method of use
A - Výsledek využívá pouze poskytovatel
Usage type
N - Využití výsledku jiným subjektem je možné bez nabytí licence (výsledek není licencován)