Spontaneous regression of tumour and the role of microbial infection - possibilities for cancer treatment
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F16%3A00460687" target="_blank" >RIV/67985904:_____/16:00460687 - isvavai.cz</a>
Alternative codes found
RIV/00064211:_____/16:N0000038
Result on the web
<a href="http://dx.doi.org/10.1097/CAD.0000000000000337" target="_blank" >http://dx.doi.org/10.1097/CAD.0000000000000337</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/CAD.0000000000000337" target="_blank" >10.1097/CAD.0000000000000337</a>
Alternative languages
Result language
angličtina
Original language name
Spontaneous regression of tumour and the role of microbial infection - possibilities for cancer treatment
Original language description
This review deals with the role of microorganisms in spontaneous regression of a tumour. Spontaneous cancer regression is a phenomenon that has been described for many centuries. One of the most well known methods of inducing spontaneous regression of cancer is the application of Coley's toxin (heat-killed Streptococcus pyogenes and Serratia marcescens), which has been used for the successful treatment of sarcomas, carcinomas, lymphomas, myelomas and melanomas. In clinical practice, the use of Bacillus Calmette-Guerin vaccine for the treatment of superficial urinary bladder cancer is the most common instance of the application of microorganisms for the treatment of cancer. This review provides further information on other tested bacteria - Clostridium spp., Bifidobacterium spp., Lactobacillus spp. and Salmonella spp. - in this field of study. Among new age methods, bactofection, alternative gene therapy, combination bacteriolytic therapy and bacteria-directed enzyme prodrug therapy are some of the potential cancer treatment modalities that use microorganisms. We have also provided information about the interconnection among microorganisms, immune system response, and the possible mechanisms involved in the spontaneous regression of tumours.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/ED2.1.00%2F03.0124" target="_blank" >ED2.1.00/03.0124: ExAM Experimental Animal Models</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Anti-cancer Drugs
ISSN
0959-4973
e-ISSN
—
Volume of the periodical
27
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
269-277
UT code for WoS article
000373774900001
EID of the result in the Scopus database
2-s2.0-84961200129