Spontaneous regression of malignant melanoma - is it based on the interplay between host immune system and melanoma antigens?

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F17%3A00480626" target="_blank" >RIV/67985904:_____/17:00480626 - isvavai.cz</a>
Alternative codes found
RIV/60460709:41210/17:74868 RIV/00064211:_____/17:W0000017
Result on the web
<a href="http://dx.doi.org/10.1097/CAD.0000000000000526" target="_blank" >http://dx.doi.org/10.1097/CAD.0000000000000526</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/CAD.0000000000000526" target="_blank" >10.1097/CAD.0000000000000526</a>

Result language
angličtina
Original language name
Spontaneous regression of malignant melanoma - is it based on the interplay between host immune system and melanoma antigens?
Original language description
Malignant melanoma (MM) is the most aggressive and uneasily treatable form of skin cancer. Up to 90% of deaths because of skin tumours are estimated to be caused by this malignancy. Spontaneous regression is described as a partial or complete disappearance of cancer. It can be defined if the clinical and histological diagnosis of malignancy is verified and any therapeutic intervention potentially inducing mechanisms leading to regression has not been applied. Regression occurs more frequently in melanoma than in other types of tumours, it is reported to be six times higher than in other malignancies. Up to 50% of primary MM is reported to undergo spontaneous regression. However, spontaneous regression of the metastatic form of tumour is a rare phenomenon observed in only 0.23% of cases. The most frequently mentioned factors leading to spontaneous regression of MM are operative trauma, infection, vaccination (BCG and rabies vaccines) and immunological factors. Other well-documented circumstances associated with regression of metastatic MM include blood transfusion and various endocrine factors.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30102 - Immunology

Project
<a href="/en/project/LO1609" target="_blank" >LO1609: Models of the Serious Human Diseases: Traumatic Spinal Cord Injury, Huntington’s Disease, Melanoma and Infertility</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)