Genome Compositional Organization in Gars Shows More Similarities to Mammals than to Other Ray-Finned Fish

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F17%3A00481774" target="_blank" >RIV/67985904:_____/17:00481774 - isvavai.cz</a>

Alternative codes found

RIV/60076658:12520/17:43895898 RIV/00216208:11310/17:10364657

Result on the web

<a href="http://dx.doi.org/10.1002/jez.b.22719" target="_blank" >http://dx.doi.org/10.1002/jez.b.22719</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jez.b.22719" target="_blank" >10.1002/jez.b.22719</a>

Result language

angličtina

Original language name

Genome Compositional Organization in Gars Shows More Similarities to Mammals than to Other Ray-Finned Fish

Original language description

Genomic GC content can vary locally, and GC-rich regions are usually associated with increased DNA thermostability in thermophilic prokaryotes and warm-blooded eukaryotes. Among vertebrates, fish and amphibians appeared to possess a distinctly less heterogeneous AT/GC organization in their genomes, whereas cytogenetically detectable GC heterogeneity has so far only been documented in mammals and birds. The subject of our study is the gar, an ancient living fossil of a basal ray-finned fish lineage, known from the Cretaceous period. We carried out cytogenomic analysis in two gar genera (Atractosteus and Lepisosteus) uncovering a GC chromosomal pattern uncharacteristic for fish. Bioinformatic analysis of the spotted gar (Lepisosteus oculatus) confirmed a GC compartmentalization on GC profiles of linkage groups. This indicates a rather mammalian mode of compositional organization on gar chromosomes. Gars are thus the only analyzed extant ray-finned fishes with a GC compartmentalized genome. Since gars are cold-blooded anamniotes, our results contradict the generally accepted hypothesis that the phylogenomic onset of GC compartmentalization occurred near the origin of amniotes. Ecophysiological findings of other authors indicate a metabolic similarity of gars with mammals. We hypothesize that gars might have undergone convergent evolution with the tetrapod lineages leading to mammals on both metabolic and genomic levels. Their metabolic adaptations might have left footprints in their compositional genome evolution, as proposed by the metabolic rate hypothesis. The genome organization described here in gars sheds new light on the compositional genome evolution in vertebrates generally and contributes to better understanding of the complexities of the mechanisms involved in this process.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10613 - Zoology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution Additional Title Information

ISSN

1552-5007

e-ISSN

—

Volume of the periodical

328

Issue of the periodical within the volume

7

Country of publishing house

US - UNITED STATES

Number of pages

13

Pages from-to

607-619

UT code for WoS article

000413586500003

EID of the result in the Scopus database

2-s2.0-85007495631