Importance of ERK1/2 in Regulation of Protein Translation during Oocyte Meiosis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F18%3A00492350" target="_blank" >RIV/67985904:_____/18:00492350 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11310/18:10403777

Result on the web

<a href="http://dx.doi.org/10.3390/ijms19030698" target="_blank" >http://dx.doi.org/10.3390/ijms19030698</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ijms19030698" target="_blank" >10.3390/ijms19030698</a>

Result language

angličtina

Original language name

Importance of ERK1/2 in Regulation of Protein Translation during Oocyte Meiosis

Original language description

Although the involvement of the extracellular signal-regulated kinases 1 and 2 (ERK1/2) pathway in the regulation of cytostatic factor (CSF) aktivity, as well as in microtubules organization during meiotic maturation of oocytes, has already been described in detail, rather less attention has been paid to the role of ERK1/2 in the regulation of mRNA translation. However, important data on the role of ERK1/2 in translation during oocyte meiosis have been documented. This review focuses on recent findings regarding the regulation of translation and the role of ERK1/2 in this process in the meiotic cycle of mammalian oocytes. The specific role of ERK1/2 in the regulation of mammalian target of rapamycin (mTOR), eukaryotic translation initiation factor 4E (eIF4E) and cytoplasmic polyadenylation element binding protein 1 (CPEB1) activity is addressed along with additional focus on the other key players involved in protein translation.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10608 - Biochemistry and molecular biology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Molecular Sciences

ISSN

1422-0067

e-ISSN

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Volume of the periodical

19

Issue of the periodical within the volume

3

Country of publishing house

CH - SWITZERLAND

Number of pages

21

Pages from-to

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UT code for WoS article

000428309800055

EID of the result in the Scopus database

2-s2.0-85042787387