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Isolating Chromosomes of the Komodo Dragon: New Tools for Comparative Mapping and Sequence Assembly

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F19%3A00511982" target="_blank" >RIV/67985904:_____/19:00511982 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11310/19:10406965

  • Result on the web

    <a href="https://asep.lib.cas.cz/arl-cav/cs/csg/?repo=crepo1&key=41048410983" target="_blank" >https://asep.lib.cas.cz/arl-cav/cs/csg/?repo=crepo1&key=41048410983</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1159/000496171" target="_blank" >10.1159/000496171</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Isolating Chromosomes of the Komodo Dragon: New Tools for Comparative Mapping and Sequence Assembly

  • Original language description

    We developed new tools to build a high-quality chromosomal map of the Komodo dragon (Varanus komodoensis) available for cross-species phylogenomic analyses. First, we isolated chromosomes by flow sorting and determined the chromosome content of each flow karyotype peak by FISH. We then isolated additional Komodo dragon chromosomes by microdissection and amplified chromosome-specific DNA pools. The chromosome-specific DNA pools can be sequenced, assembled, and mapped by next-generation sequencing technology. The chromosome-specific paint probes can be used to investigate karyotype evolution through cross-species chromosome painting. Overall, the set of chromosome-specific DNA pools of V. komodoensis provides new tools for detailed phylogenomic analyses of Varanidae and squamates in general.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10613 - Zoology

Result continuities

  • Project

    <a href="/en/project/GJ17-22141Y" target="_blank" >GJ17-22141Y: Evolution of sex chromosomes in toxicoferan reptiles</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Cytogenetic and Genome Research

  • ISSN

    1424-8581

  • e-ISSN

  • Volume of the periodical

    157

  • Issue of the periodical within the volume

    1-2

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    9

  • Pages from-to

    123-131

  • UT code for WoS article

    000466128800013

  • EID of the result in the Scopus database

    2-s2.0-85060205083