Examination of the Spatial Structure of Pigs' Melanoma in Tissue Sections Based on Histology and Mass Spectrometry

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F19%3A00517391" target="_blank" >RIV/67985904:_____/19:00517391 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-981-10-9035-6_46" target="_blank" >http://dx.doi.org/10.1007/978-981-10-9035-6_46</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-981-10-9035-6_46" target="_blank" >10.1007/978-981-10-9035-6_46</a>

Result language
angličtina
Original language name
Examination of the Spatial Structure of Pigs' Melanoma in Tissue Sections Based on Histology and Mass Spectrometry
Original language description
We examine the spatial structure of the melanoma in tissue sections. The pigs melanoma was examined in 10 tissue samples obtained from animals of age between 4 and 22 weeks. The tissue sections were measured by light microscopy and Laser Ablation Ion Inductively Coupled Plasma Mass Spectrometry to obtain spatial metal (Cu, Zn) distribution. The exploratory analysis of the tissue sections indicates there is clearly a pattern in the spatial structure. Different projections of the spatial structure of the melanoma are obtained by the different measurement methods. The spectral clustering on the data was utilized to describe the structure in the data. According to the clustering results, there are distinct clusters of observations in the histological data. The spatial elemental distribution of the metals Cu and Zn cannot be clustered -the data form one compact cluster. The clustering of the histological images produces clusters which are related to the annotation of the biological samples in broader terms -the differences between fibrous and cancerous tissue.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING 2018
ISBN
978-981-10-9035-6
ISSN
—
e-ISSN
—
Number of pages
5
Pages from-to
255-259
Publisher name
Springer
Place of publication
Prague
Event location
Prague
Event date
Jun 3, 2018
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000450908300046

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