Extracellular vesicles: a potential source of biomarkers in neurodegenerative diseases

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F20%3A00536530" target="_blank" >RIV/67985904:_____/20:00536530 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Extracellular vesicles: a potential source of biomarkers in neurodegenerative diseases

Original language description

Extracellular vesicles (EVs) are mediators of intercellular communication, which can transfer protein, RNA or small molecules into recipient cells and change their phenotype. In the central nervous system, EVs play roles in various physiological functions, including development, synaptic transmission or neuronal protection and regeneration. In neurodegenerative diseases, EVs may participate in transfer of misfolded proteins into healthy cells but possess also diagnostic/prognostic and therapeutic potential. Research of neurodegenerative disease pathophysiology is limited to studies on cellular models, experimental animals or post-mortem tissues. EVs offer a valuable alternative to access the diseased nervous system with minimal invasiveness.

Czech name

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Czech description

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Type

C - Chapter in a specialist book

CEP classification

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OECD FORD branch

10608 - Biochemistry and molecular biology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name

Translational Research in Serious Human Diseases

ISBN

978-80-200-3158-7

Number of pages of the result

9

Pages from-to

123-131

Number of pages of the book

271

Publisher name

Academia

Place of publication

Praha

UT code for WoS chapter

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