Divergent gut microbiota in two closely related house mouse subspecies under common garden conditions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F22%3A00561123" target="_blank" >RIV/67985904:_____/22:00561123 - isvavai.cz</a>
Alternative codes found
RIV/68081766:_____/22:00560422 RIV/00216208:11310/22:10447189
Result on the web
<a href="https://asep.lib.cas.cz/arl-cav/cs/csg/?repo=crepo1&key=90812963689" target="_blank" >https://asep.lib.cas.cz/arl-cav/cs/csg/?repo=crepo1&key=90812963689</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/femsec/fiac078" target="_blank" >10.1093/femsec/fiac078</a>
Alternative languages
Result language
angličtina
Original language name
Divergent gut microbiota in two closely related house mouse subspecies under common garden conditions
Original language description
The gastrointestinal microbiota (GM) is considered an important component of the vertebrate holobiont. GM-host interactions influence the fitness of holobionts and are, therefore, an integral part of evolution. The house mouse is a prominent model for GM-host interactions, and evidence suggests a role for GM in mouse speciation. However, previous studies based on short 16S rRNA GM profiles of wild house mouse subspecies failed to detect GM divergence, which is a prerequisite for the inclusion of GM in Dobzhansky-Muller incompatibilities. Here, we used standard 16S rRNA GM profiling in two mouse subspecies, Mus musculus musculus and M. m. domesticus, including the intestinal mucosa and content of three gut sections (ileum, caecum, and colon). We reduced environmental variability by sampling GM in the offspring of wild mice bred under seminatural conditions. Although the breeding conditions allowed a contact between the subspecies, we found a clear differentiation of GM between them, in all three gut sections. Differentiation was mainly driven by several Helicobacters and two H. ganmani variants showed a signal of codivergence with their hosts. Helicobacters represent promising candidates for studying GM-host coadaptations and the fitness effects of their interactions.nnSequencing of bacterial 16S rRNA gene reveales differences in gut microbiota between two house mouse subspecies (mainly formed by genus Helicobacter), their gut segments, and between gut mucosa and content.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
FEMS Microbiology Ecology
ISSN
0168-6496
e-ISSN
1574-6941
Volume of the periodical
98
Issue of the periodical within the volume
8
Country of publishing house
GB - UNITED KINGDOM
Number of pages
13
Pages from-to
fiac078
UT code for WoS article
000840866400001
EID of the result in the Scopus database
2-s2.0-85136908934