A pilot study: Exploring the influence of COVID-19 on cardiovascular physiology and retinal microcirculation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F23%3A00575032" target="_blank" >RIV/67985904:_____/23:00575032 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/23:00133041
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0026286223001140?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0026286223001140?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.mvr.2023.104588" target="_blank" >10.1016/j.mvr.2023.104588</a>
Alternative languages
Result language
angličtina
Original language name
A pilot study: Exploring the influence of COVID-19 on cardiovascular physiology and retinal microcirculation
Original language description
Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the cardiovascular sys-tem. The current study investigated changes in heart rate (HR), blood pressure (BP), pulse wave velocity (PWV), and microcirculation in patients recovering from Coronavirus disease 2019 (COVID-19) infection.Methodology: Out of 43 initially contacted COVID-19 patients, 35 (30 males, 5 females, age: 60 & PLUSMN, 10 years, and body mass index (BMI): 31.8 & PLUSMN, 4.9) participated in this study. Participants were seen on two occasions after hospital discharge, the baseline measurements were collected, either on the day of hospital discharge if a negative PCR test was obtained, or on the 10th day after hospitalization if the PCR test was positive. The second measurements were done 60 days after hospitalization. The vascular measurements were performed using the VICORDER & REG, device and a retinal blood vessel image analysis. Results: A significant increase in systolic BP (SBP) (from 142 mmHg, SD: 15, to 150 mmHg, SD: 19, p = 0.041), reduction in HR (from 76 bpm, SD: 15, to 69 bpm, SD: 11, p = 0.001), and narrower central retinal vein equivalent (CRVE) (from 240.94 & mu,m, SD: 16.05, to 198.05 & m,m, SD: 17.36, p = 0.013) were found. Furthermore, the trends of increasing PWV (from 11 m/s, SD: 3, to 12 m/s, SD: 3, p = 0.095) and decreasing CRAE (from 138.87 & mu,m, SD: 12.19, to 136.77 & mu,m, SD: 13.19, p = 0.068) were recorded.Conclusion: The present study investigated cardiovascular changes following COVID-19 infection at two-time points after hospital discharge (baseline measurements and 60 days post-hospitalization). Significant changes were found in systolic blood pressure, heart rate, and microvasculature indicating that vascular adaptations may be ongoing even weeks after hospitalization from COVID-19 infection. Future studies could involve conducting additional interim assessments during the active infection and post-infection periods.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30303 - Infectious Diseases
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Microvascular Research
ISSN
0026-2862
e-ISSN
1095-9319
Volume of the periodical
150
Issue of the periodical within the volume
Nov 23
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
7
Pages from-to
104588
UT code for WoS article
001049715900001
EID of the result in the Scopus database
2-s2.0-85165195733