Microfluidic device for enhancement and analysis of osteoblast differentiation in three-dimensional cell cultures

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F23%3A00580038" target="_blank" >RIV/67985904:_____/23:00580038 - isvavai.cz</a>
Alternative codes found
RIV/68081715:_____/23:00580038 RIV/00216224:14310/23:00132710
Result on the web
<a href="https://doi.org/10.1186/s13036-023-00395-z" target="_blank" >https://doi.org/10.1186/s13036-023-00395-z</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s13036-023-00395-z" target="_blank" >10.1186/s13036-023-00395-z</a>

Result language
angličtina
Original language name
Microfluidic device for enhancement and analysis of osteoblast differentiation in three-dimensional cell cultures
Original language description
In this study, we consequently developed, optimized and characterized an advanced perfused microfluidic platform to improve the reliability of 3D bone cell cultivation and to enhance aspects of bone tissue maturation in vitro. Moreover, biomechanical stimulation generated by fluid flow inside the arrayed chamber, was used to mimic a more dynamic cell environment emulating a highly vascularized bone we expected to improve the osteogenic 3D microenvironment in the developed multifunctional spheroid-array platform.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10601 - Cell biology

Project
<a href="/en/project/GA20-00726S" target="_blank" >GA20-00726S: Investigation of novel functions of caspases by their simultaneous quantification in individual cells</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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