Patterns of MHC-dependent mate selection in humans and nonhuman primates: a meta-analysis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985939%3A_____%2F17%3A00509045" target="_blank" >RIV/67985939:_____/17:00509045 - isvavai.cz</a>

Alternative codes found

RIV/68081766:_____/17:00465784 RIV/00216208:11310/17:10368580

Result on the web

<a href="http://hdl.handle.net/11104/0299855" target="_blank" >http://hdl.handle.net/11104/0299855</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/mec.13920" target="_blank" >10.1111/mec.13920</a>

Result language

angličtina

Original language name

Patterns of MHC-dependent mate selection in humans and nonhuman primates: a meta-analysis

Original language description

Genes of the major histocompatibility complex (MHC) in vertebrates are integral for effective adaptive immune response and are associated with sexual selection. Evidence from a range of vertebrates supports MHC-based preference for diverse and dissimilar mating partners, but evidence from human mate choice studies has been disparate and controversial. Methodologies and sampling peculiarities specific to human studies make it difficult to know whether wide discrepancies in results among human populations are real or artefact. To better understand what processes may affect MHC-mediated mate choice across humans and nonhuman primates, we performed phylogenetically controlled meta-analyses using 58 effect sizes from 30 studies across seven primate species. Primates showed a general trend favouring more MHC-diverse mates, which was statistically significant for humans. In contrast, there was no tendency for MHC-dissimilar mate choice, and for humans, we observed effect sizes indicating selection of both MHC-dissimilar and MHC-similar mates. Focusing on MHC-similar effect sizes only, we found evidence that preference for MHC similarity was an artefact of population ethnic heterogeneity in observational studies but not among experimental studies with more control over sociocultural biases. This suggests that human assortative mating biases may be responsible for some patterns of MHC-based mate choice. Additionally, the overall effect sizes of primate MHC-based mating preferences are relatively weak (Fisher's Z correlation coefficient for dissimilarity Zr=0.044, diversity Zr=0.153), calling for careful sampling design in future studies. Overall, our results indicate that preference for more MHC-diverse mates is significant for humans and likely conserved across primates.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10618 - Ecology

Project

<a href="/en/project/EE2.3.30.0048" target="_blank" >EE2.3.30.0048: Integration of the experimental and population biology using new methods of interdisciplinary issues - the way to excellence with young scientists</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Molecular Ecology

ISSN

0962-1083

e-ISSN

—

Volume of the periodical

26

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

21

Pages from-to

668-688

UT code for WoS article

000393944000019

EID of the result in the Scopus database

2-s2.0-85006341526