Patterns of MHC-dependent mate selection in humans and non-human primates: a meta-analysis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081766%3A_____%2F17%3A00465784" target="_blank" >RIV/68081766:_____/17:00465784 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11310/17:10368580 RIV/67985939:_____/17:00509045

Result on the web

<a href="http://dx.doi.org/10.1111/mec.13920" target="_blank" >http://dx.doi.org/10.1111/mec.13920</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/mec.13920" target="_blank" >10.1111/mec.13920</a>

Result language

angličtina

Original language name

Patterns of MHC-dependent mate selection in humans and non-human primates: a meta-analysis

Original language description

Genes of the major histocompatibility complex (MHC) in vertebrates are integral for effective adaptive immune response and are associated with sexual selection. Evidence from a range of vertebrates supports MHC-based preference for diverse and dissimilar mating partners, but evidence from human mate choice studies has been disparate and controversial. Methodologies and sampling peculiarities specific to human studies make it difficult to know whether wide discrepancies in results among human populations are real or artifact. To better understand what processes may affect MHC-mediated mate choice across humans and non-human primates we performed phylogenetically controlled meta-analyses using 58 effect sizes from 30 studies across 7 primate species. Primates showed a general trend favoring more MHC-diverse mates, which was statistically significant for humans. In contrast, there was no tendency for MHCdissimilar mate choice, and for humans, we observed effect sizes indicating selection of both MHCdissimilar and MHC-similar mates. Focusing on MHC-similar effect sizes only, we found evidence that preference for MHC-similarity was an artifact of population ethnic heterogeneity in observational studies but not among experimental studies with more control over socio-cultural biases. This suggests that human assortative mating biases may be responsible for some patterns of MHC-based mate choice. Additionally, the overall effect sizes of primate MHC-based mating preferences are relatively weak (Fisher’s Z correlation coefficient for dissimilarity Zr = 0.044, diversity Zr = 0.153), calling for careful sampling design in future studies. Overall, our results indicate that preference for more MHC diverse mates is significant for humans and likely conserved across primates.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Molecular Ecology

ISSN

0962-1083

e-ISSN

—

Volume of the periodical

26

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

21

Pages from-to

668-688

UT code for WoS article

000393944000019

EID of the result in the Scopus database

2-s2.0-85006341526