Modulation of Radioprotective Effects of Respiratory Hypoxia by Changing the Duration of Hypoxia before Irradiation and by Combining Hypoxia and Administration of Hemopoiesis-Stimulating Agents.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F01%3A17013031" target="_blank" >RIV/68081707:_____/01:17013031 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Modulation of Radioprotective Effects of Respiratory Hypoxia by Changing the Duration of Hypoxia before Irradiation and by Combining Hypoxia and Administration of Hemopoiesis-Stimulating Agents.

Original language description

Radioprotective effects of respiratory hypoxia on hematopoiesis and possibilities of enhancing these effects by granulocyte-macrophage colony-stimulating factor or dextran sulfate were analysed in gamma-irradiated mice. Hypoxia improved the recovery of hematopoiesis and mitigated lethal effects of gamma-rays. Enhancement of proliferative activity in hematopoietic tissues by hematopoietic stimulators increased the radioprotective effects of hypoxia. Adaptation of experimental animals to hypoxic conditions was found to reduce the radioprotective effects without influencing tissue partial oxygen pressure lowered by hypoxia

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BO - Biophysics

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2001

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Strahlentherapie und Onkologie

ISSN

0179-7158

e-ISSN

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Volume of the periodical

177

Issue of the periodical within the volume

9

Country of publishing house

DE - GERMANY

Number of pages

8

Pages from-to

474-481

UT code for WoS article

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EID of the result in the Scopus database

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