In vitro proliferation of fibrosarcoma cells depends on intact functions of lipoxygenases and cytochrome P-450-monooxygenase
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F04%3A00104630" target="_blank" >RIV/68081707:_____/04:00104630 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
In vitro proliferation of fibrosarcoma cells depends on intact functions of lipoxygenases and cytochrome P-450-monooxygenase
Original language description
Proliferation of mouse fibrosarcoma cells G:5:113 was studied in vitro after affecting particular pathways of arachidonic acid metabolism by selected inhibitors. It was found that the proliferation ability of these cells depended on intact functions of 5-lipoxygenase, 12-lipoxygenase, and cytochrome P-450-monoxygenases, and that the effects of inhibitors of these enzymes did not include regulation of apoptosis.
Czech name
Proliferace fibrosarkomových buněk in vitro je závislá na zachování funkčnosti lipoxygenáz a cytochrom P-450 monooxygenázy
Czech description
Byla studována proliferace myších fibrosarkomových buněk G:5:113 in vitro v podmínkách modulace metabolismu kyseliny arachidonové vybranými inhibitory. Bylo zjištěno že proliferační schopnost těchto buněk je závislá na zachování funkčnosti 5-lipoxygenázy, 12-lipoxygenázy a cytochrom P-450 monooxygenázy, a že efekty vyvolané inhibitory těchto enzymů nezahrnují řízení apoptózy.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cancer Investigation
ISSN
0735-7907
e-ISSN
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Volume of the periodical
22
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
14
Pages from-to
234-247
UT code for WoS article
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EID of the result in the Scopus database
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