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The influence of carvedilol on the production of reactive oxygen and nitrogen species by phagocytes

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F05%3A00026063" target="_blank" >RIV/68081707:_____/05:00026063 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The influence of carvedilol on the production of reactive oxygen and nitrogen species by phagocytes

  • Original language description

    Carvedilol (0.1 uM - 100 uM) dose-dependently inhibited both the spontaneous and the activated CL of phagocytes, although the effect of carvedilol was also dependent on the type of activator. This suggests that carvedilol, besides its antioxidative properties, affects the metabolic pathway of NADPH oxidase activation.

  • Czech name

    Vliv carvedilolu na produkci kyslíkových a dusíkových metabolitů fagocyty

  • Czech description

    Carvedilol (0,1 uM - 100 uM) v koncentrační závislosti snižoval spontánní a také aktivovanou produkci reaktivních kyslíkových metabolitů měřenou chemiluminescenční metodou. Stupeň této inhibice byl závislý na typu použitého aktivátoru. To nasvědčuje tomu, že carvedilol, vedle svých antioxidačních vlastností, zasahuje metabolickou cestu aktivace NADPH oxidázy.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biologia

  • ISSN

    0006-3088

  • e-ISSN

  • Volume of the periodical

    53

  • Issue of the periodical within the volume

    -

  • Country of publishing house

    SK - SLOVAKIA

  • Number of pages

    9

  • Pages from-to

    1-9

  • UT code for WoS article

  • EID of the result in the Scopus database