Role of aryl hydrocarbon receptor in modulation of the expression of the hypoxia marker carbonic anhydrase IX
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F09%3A00323910" target="_blank" >RIV/68081707:_____/09:00323910 - isvavai.cz</a>
Alternative codes found
RIV/00027162:_____/09:#0000540
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Role of aryl hydrocarbon receptor in modulation of the expression of the hypoxia marker carbonic anhydrase IX
Original language description
The results from the present study suggest that treatment with, an AhR ligand, reduces hypoxic induction of both CA IX mRNA and protein expression. ARNT is critical for both hypoxic induction and the TCDD-mediated inhibition of CA IX expression.
Czech name
Úloha receptoru pro aromatické uhlovodíky v modulaci exprese hypoxického markeru karbonické anhydrázy IX
Czech description
Výsledky této studie ukazují, že působení 2,3,7,8-tetrachlórdibenzo-p-dioxinu (TCDD), ligandu AhR, potlačuje hypoxií indukovanou expresi CA IX mRNA a proteinu. ARNT hraje kritickou úlohu jak v indukci CA IX prostřednictvím hypoxie, tak v jejím potlačeníTCDD.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biochemical Journal
ISSN
0264-6021
e-ISSN
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Volume of the periodical
419
Issue of the periodical within the volume
-
Country of publishing house
GB - UNITED KINGDOM
Number of pages
7
Pages from-to
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UT code for WoS article
000265196900018
EID of the result in the Scopus database
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