Human fetal colon cells and colon cancer cells respond differently to butyrate and PUFAs

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F09%3A00332328" target="_blank" >RIV/68081707:_____/09:00332328 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Human fetal colon cells and colon cancer cells respond differently to butyrate and PUFAs

Original language description

Comparing human colon epithelial cell lines of fetal (FHC) and adenocarcinoma (HT-29, HCT-116) origin, we detected significant differences in proliferation, differentiation, and apoptotic response to the treatment of sodium butyrate (NaBt), arachidonic or docosahexaenoic acids, and their combination. Our results support the concept of modulation of NaBt effects by polyunsaturated fatty acids, especially of omega-3 type, in colonic cells in vitro with diverse impact in cell lines derived from normal or neoplastic epithelium.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BO - Biophysics

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Molecular Nutrition & Food Research

ISSN

1613-4125

e-ISSN

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Volume of the periodical

53

Issue of the periodical within the volume

1

Country of publishing house

DE - GERMANY

Number of pages

12

Pages from-to

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UT code for WoS article

000271475300013

EID of the result in the Scopus database

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