Insight into G-DNA structural polymorphism and folding from sequence and loop connectivity through free energy analysis

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F11%3A00365891" target="_blank" >RIV/68081707:_____/11:00365891 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1021/ja107805r" target="_blank" >http://dx.doi.org/10.1021/ja107805r</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/ja107805r" target="_blank" >10.1021/ja107805r</a>

Result language
angličtina
Original language name
Insight into G-DNA structural polymorphism and folding from sequence and loop connectivity through free energy analysis
Original language description
The lengths of G-tracts and their connecting loop sequences determine G-quadruplex folding and stability. Here, single-loop G-quadruplexes were investigated using explicit solvent molecular dynamics (MD) simulations to characterize the effect of loop length, loop sequence, and G-tract length on the folding topologies and stability of G-quadruplexes.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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