Cation binding to 15-TBA quadruplex DNA is a multiple-pathway cation-dependent process

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F11%3A00372033" target="_blank" >RIV/68081707:_____/11:00372033 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1093/nar/gkr639" target="_blank" >http://dx.doi.org/10.1093/nar/gkr639</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/nar/gkr639" target="_blank" >10.1093/nar/gkr639</a>

Result language

angličtina

Original language name

Cation binding to 15-TBA quadruplex DNA is a multiple-pathway cation-dependent process

Original language description

A combination of explicit solvent molecular dynamics simulation, hybrid quantum mechanics/molecular mechanics approach and isothermal tetration calorimetry was used to investigate the atomistic picture of ion binding to 15-mer thrombin-binding quadruplexDNA (G-DNA) aptamer. Binding of ions to G-DNA is complex multiple pathway process, which is strongly affected by the type of the cation.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BO - Biophysics

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nucleic Acids Research

ISSN

0305-1048

e-ISSN

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Volume of the periodical

39

Issue of the periodical within the volume

22

Country of publishing house

GB - UNITED KINGDOM

Number of pages

14

Pages from-to

9789-9802

UT code for WoS article

000298186000034

EID of the result in the Scopus database

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