Antitumor carboplatin is more toxic in tumor cells when photoactivated: enhanced DNA binging
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F12%3A00381591" target="_blank" >RIV/68081707:_____/12:00381591 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s00775-012-0906-z" target="_blank" >http://dx.doi.org/10.1007/s00775-012-0906-z</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00775-012-0906-z" target="_blank" >10.1007/s00775-012-0906-z</a>
Alternative languages
Result language
angličtina
Original language name
Antitumor carboplatin is more toxic in tumor cells when photoactivated: enhanced DNA binging
Original language description
It was found that carboplatin was converted to species capable of enhanced DNA binding by UVA irradiation and consequently its toxicity in cancer cells was markedly enhanced. Recent advances in laser and fiber-optic technologies make it possible to irradiate also internal organs with light of highly defined intensity and wavelength. Thus, carboplatin is a candidate for use in photoactivated cancer chemotherapy.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Biological Inorganic Chemistry
ISSN
0949-8257
e-ISSN
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Volume of the periodical
17
Issue of the periodical within the volume
6
Country of publishing house
DE - GERMANY
Number of pages
8
Pages from-to
891-898
UT code for WoS article
000306731100005
EID of the result in the Scopus database
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