3,6-Bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F12%3A00388509" target="_blank" >RIV/68081707:_____/12:00388509 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.ejmech.2012.09.020" target="_blank" >http://dx.doi.org/10.1016/j.ejmech.2012.09.020</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ejmech.2012.09.020" target="_blank" >10.1016/j.ejmech.2012.09.020</a>
Alternative languages
Result language
angličtina
Original language name
3,6-Bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents
Original language description
A series of 3,6-bis(3-alkylguanidino) acridines was prepared and the interaction of these novel compounds with calf thymus DNA was investigated with UV-vis, fluorescence and circular dichroism spectroscopy, in addition to DNA melting techniques. The results have indicated that studied compounds act as effective DNA- -intercalating agents.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Journal of Medicinal Chemistry
ISSN
0223-5234
e-ISSN
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Volume of the periodical
57
Issue of the periodical within the volume
2012
Country of publishing house
FR - FRANCE
Number of pages
13
Pages from-to
283-295
UT code for WoS article
000312621700030
EID of the result in the Scopus database
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