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DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F09%3A00320869" target="_blank" >RIV/68081707:_____/09:00320869 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media

  • Original language description

    DNA modifications by new dinuclear RuII arene compounds were studied. The complexes bind DNA forming intrastrand and interstrand cross-links in one DNA molecule. An intriguing aspect of the DNA-binding mode of these dinuclear RuII compounds is that theycan crosslink two DNA duplexes and also proteins to DNA.

  • Czech name

    Interakce DNA s protinádorově aktivními dinukleárními RuII komplexy in vitro

  • Czech description

    Byly studovány modifikace DNA sérií nových dinukleárních Ru komplexů. Tyto komplexy tvoří na molekule DNA vnitrořetězcové i meziřetězcové můstky. Kromě toho jsou schopny vytvářet také můstky mezi dvěma molekulami DNA nebo DNA a proteiny.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biochemical Pharmacology

  • ISSN

    0006-2952

  • e-ISSN

  • Volume of the periodical

    77

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    11

  • Pages from-to

  • UT code for WoS article

    000262935900007

  • EID of the result in the Scopus database