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Palindrome analyser - A new web-based server for predicting and evaluating inverted repeats in nucleotide sequences

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F16%3A00464948" target="_blank" >RIV/68081707:_____/16:00464948 - isvavai.cz</a>

  • Alternative codes found

    RIV/62156489:43110/16:43909543 RIV/00216305:26210/16:PU120369

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.bbrc.2016.09.015" target="_blank" >http://dx.doi.org/10.1016/j.bbrc.2016.09.015</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.bbrc.2016.09.015" target="_blank" >10.1016/j.bbrc.2016.09.015</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Palindrome analyser - A new web-based server for predicting and evaluating inverted repeats in nucleotide sequences

  • Original language description

    DNA cruciform structures play an important role in the regulation of natural processes including gene replication and expression, as well as nucleosome structure and recombination. They have also been implicated in the evolution and development of diseases such as cancer and neurodegenerative disorders. Cruciform structures are formed by inverted repeats, and their stability is enhanced by DNA supercoiling and protein binding. They have received broad attention because of their important roles in biology. Computational approaches to study inverted repeats have allowed detailed analysis of genomes. However, currently there are no easily accessible and user-friendly tools that can analyse inverted repeats, especially among long nucleotide sequences. We have developed a web-based server, Palindrome analyser, which is a user-friendly application for analysing inverted repeats in various DNA (or RNA) sequences including genome sequences and oligonucleotides. It allows users to search and retrieve desired gene/nucleotide sequence entries from the NCBI databases, and provides data on length, sequence, locations and energy required for cruciform formation. Palindrome analyser also features an interactive graphical data representation of the distribution of the inverted repeats, with options for sorting according to the length of inverted repeat, length of loop, and number of mismatches. Palindrome analyser can be accessed at http://bioinformatics.ibp.cz. (C) 2016 Elsevier Inc. All rights reserved.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA15-21855S" target="_blank" >GA15-21855S: Influence of conformation motifs and epigenetic modifications to DNA binding properties of p53 family proteins</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biochemical and Biophysical Research Communications

  • ISSN

    0006-291X

  • e-ISSN

  • Volume of the periodical

    478

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    1739-1745

  • UT code for WoS article

    000384390200039

  • EID of the result in the Scopus database