Distinguishing glycan isomers by voltammetry. Modification of 2,3-sialyllactose and 2,6-sialyllactose by osmium(VI) complexes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F17%3A00486056" target="_blank" >RIV/68081707:_____/17:00486056 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.elecom.2017.10.014" target="_blank" >http://dx.doi.org/10.1016/j.elecom.2017.10.014</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.elecom.2017.10.014" target="_blank" >10.1016/j.elecom.2017.10.014</a>
Alternative languages
Result language
angličtina
Original language name
Distinguishing glycan isomers by voltammetry. Modification of 2,3-sialyllactose and 2,6-sialyllactose by osmium(VI) complexes
Original language description
Carbohydrate components in glycoproteins play a critical role in health and disease and specificity of glycoprotein biomarkers can be greatly enhanced by analysis of their sugar components containing frequently different isomers. We show that two glycan isomers, 2,3-sialyllactose and 2,6-sialyllactose (important in cancer), can be distinguished voltammetrically after their modification with osmium(VI) complexes. Using SWV at different frequencies and CV at different scan rates we found conditions for simple discrimination between these isomers at mercury and carbon electrodes.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
<a href="/en/project/GA15-15479S" target="_blank" >GA15-15479S: New tools for research and diagnostics of diseases. Microfluidic reactors and electrochemistry for analysis of proteins and their glycosylation.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electrochemistry Communications
ISSN
1388-2481
e-ISSN
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Volume of the periodical
85
Issue of the periodical within the volume
DEC2017
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
4
Pages from-to
19-22
UT code for WoS article
000415112500005
EID of the result in the Scopus database
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