Human-like telomeres in Zostera marina reveal a mode of transition from the plant to the human telomeric sequences

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F20%3A00537477" target="_blank" >RIV/68081707:_____/20:00537477 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14740/20:00114533

Result on the web

<a href="https://academic.oup.com/jxb/article-abstract/71/19/5786/5863406?redirectedFrom=fulltext" target="_blank" >https://academic.oup.com/jxb/article-abstract/71/19/5786/5863406?redirectedFrom=fulltext</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/jxb/eraa293" target="_blank" >10.1093/jxb/eraa293</a>

Result language

angličtina

Original language name

Human-like telomeres in Zostera marina reveal a mode of transition from the plant to the human telomeric sequences

Original language description

A previous study describing the genome of Zostera marina, the most widespread seagrass in the Northern hemisphere, revealed some genomic signatures of adaptation to the aquatic environment such as the loss of stomatal genes, while other functions such as an algal-like cell wall composition were acquired. Beyond these, the genome structure and organization were comparable with those of the majority of plant genomes sequenced, except for one striking feature that went unnoticed at that time: the presence of human-like instead of the expected plant-type telomeric sequences. By using different experimental approaches including fluorescence in situ hybridization (FISH), genome skimming by next-generation sequencing (NGS), and analysis of non-coding transcriptome, we have confirmed its telomeric location in the chromosomes of Z. marina. We have also identified its telomerase RNA (TR) subunit, confirming the presence of the human-type telomeric sequence in the template region. Remarkably, this region was found to be very variable even in clades with a highly conserved telomeric sequence across their species. Based on this observation, we propose that alternative annealing preferences in the template borders can explain the transition between the plant and human telomeric sequences. The further identification of paralogues of TR in several plant genomes led us to the hypothesis that plants may retain an increased ability to change their telomeric sequence. We discuss the implications of this occurrence in the evolution of telomeres while introducing a mechanistic model for the transition from the plant to the human telomeric sequences.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10611 - Plant sciences, botany

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Experimental Botany

ISSN

0022-0957

e-ISSN

—

Volume of the periodical

71

Issue of the periodical within the volume

19

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

5786-5793

UT code for WoS article

000577075400009

EID of the result in the Scopus database

2-s2.0-85100193566