Bile Acids Transporters of Enterohepatic Circulation for Targeted Drug Delivery
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F22%3A00557588" target="_blank" >RIV/68081707:_____/22:00557588 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/22:00126106
Result on the web
<a href="https://www.mdpi.com/1420-3049/27/9/2961" target="_blank" >https://www.mdpi.com/1420-3049/27/9/2961</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/molecules27092961" target="_blank" >10.3390/molecules27092961</a>
Alternative languages
Result language
angličtina
Original language name
Bile Acids Transporters of Enterohepatic Circulation for Targeted Drug Delivery
Original language description
Bile acids (BAs) are important steroidal molecules with a rapidly growing span of applications across a variety of fields such as supramolecular chemistry, pharmacy, and biomedicine. This work provides a systematic review on their transport processes within the enterohepatic circulation and related processes. The focus is laid on the description of specific or less-specific BA transport proteins and their localization. Initially, the reader is provided with essential information about BAs ' properties, their systemic flow, metabolism, and functions. Later, the transport processes are described in detail and schematically illustrated, moving step by step from the liver via bile ducts to the gallbladder, small intestine, and colon, this description is accompanied by descriptions of major proteins known to be involved in BA transport. Spillage of BAs into systemic circulation and urine excretion are also discussed. Finally, the review also points out some of the less-studied areas of the enterohepatic circulation, which can be crucial for the development of BA-related drugs, prodrugs, and drug carrier systems.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Molecules
ISSN
1420-3049
e-ISSN
1420-3049
Volume of the periodical
27
Issue of the periodical within the volume
9
Country of publishing house
CH - SWITZERLAND
Number of pages
24
Pages from-to
2961
UT code for WoS article
000794792100001
EID of the result in the Scopus database
2-s2.0-85130024499