Crystallization as a selection force at the polymerization of nucleotides in a prebiotic context

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F23%3A00576584" target="_blank" >RIV/68081707:_____/23:00576584 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14310/23:00133323

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S2589004223016772?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2589004223016772?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.isci.2023.107600" target="_blank" >10.1016/j.isci.2023.107600</a>

Result language

angličtina

Original language name

Crystallization as a selection force at the polymerization of nucleotides in a prebiotic context

Original language description

Accumulation and selection of nucleotides is one of the most challenging problems surrounding the origin of the first RNA molecules on our planet. In the current work we propose that guanosine 3',5' cyclic mono phosphate could selectively crystallize upon evaporation of an acidic prebiotic pool containing various other nucleotides. The conditions of the evaporative crystallization are fully compatible with the subsequent acid catalyzed polymerization of this cyclic nucleotide reported in earlier studies and may be relevant in a broad range of possible prebiotic environments. Albeit cytidine 3',5' cyclic monophosphate has the ability to selectively accumulate under the same conditions, its crystal structure is not likely to support polymer formation.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10401 - Organic chemistry

Project

<a href="/en/project/GA22-25057S" target="_blank" >GA22-25057S: Studies on the non-enzymatic polymerization of mildly activated nucleotide precursors</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

iScience

ISSN

2589-0042

e-ISSN

2589-0042

Volume of the periodical

26

Issue of the periodical within the volume

9

Country of publishing house

US - UNITED STATES

Number of pages

15

Pages from-to

107600

UT code for WoS article

001067991400001

EID of the result in the Scopus database

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