Prebiotic Synthesis of 3',5'-Cyclic Adenosine and Guanosine Monophosphates through Carbodiimide-Assisted Cyclization
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F23%3A00583702" target="_blank" >RIV/68081707:_____/23:00583702 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15310/23:73620885 RIV/61989592:15640/23:73620885 RIV/61989100:27740/23:10253164
Result on the web
<a href="https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.202300510" target="_blank" >https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.202300510</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/cbic.202300510" target="_blank" >10.1002/cbic.202300510</a>
Alternative languages
Result language
angličtina
Original language name
Prebiotic Synthesis of 3',5'-Cyclic Adenosine and Guanosine Monophosphates through Carbodiimide-Assisted Cyclization
Original language description
3',5'-Cyclic nucleotides play a fundamental role in modern biochemical processes and have been suggested to have played a central role at the origin of terrestrial life. In this work, we suggest that a formamide-based systems chemistry might account for their availability on the early Earth. In particular, we demonstrate that in a liquid formamide environment at elevated temperatures 3',5'-cyclic nucleotides are obtained in good yield and selectivity upon intramolecular cyclization of 5'-phosphorylated nucleosides in the presence of carbodiimides.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chembiochem
ISSN
1439-4227
e-ISSN
1439-7633
Volume of the periodical
24
Issue of the periodical within the volume
24
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
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UT code for WoS article
001084821700001
EID of the result in the Scopus database
2-s2.0-85174297224