TeloBase: a community-curated database of telomere sequences across the tree of life
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F24%3A00600734" target="_blank" >RIV/68081707:_____/24:00600734 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14740/24:00135437
Result on the web
<a href="https://academic.oup.com/nar/article/52/D1/D311/7246534?login=true" target="_blank" >https://academic.oup.com/nar/article/52/D1/D311/7246534?login=true</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/nar/gkad672" target="_blank" >10.1093/nar/gkad672</a>
Alternative languages
Result language
angličtina
Original language name
TeloBase: a community-curated database of telomere sequences across the tree of life
Original language description
Discoveries over the recent decade have demonstrated the unexpected diversity of telomere DNA motifs in nature. Ho we ver, currently available resources, Telomerase database' and Plant rDNA database', contain just fragments of all relevant literature published over decades of telomere research as they have a different primary focus and limited updates. To fill this gap, we gathered data about telomere DNA sequences from a thorough literature screen as well as by anal ysing publicly available NGS data, and we created TeloBase (http://cfb.ceitec.muni.cz/ telobase/) as a comprehensive database of information about telomere motif diversity. TeloBase is supplemented by internal taxonomy utilizing popular on-line taxonomic resources that enables in-house data filtration and graphical visualisation of telomere DNA evolutionary dynamics in the form of heat tree plots. TeloBase avoids overreliance on administrators for future data updates by having a simple form and community-curation system for application and approval, respectively, of new telomere sequences by users, which should ensure timeliness of the database and topicality .To demonstrate TeloBase utility, we examined telomere motif diversity in species from the fungal genus Aspergillus, and discovered (TTTATTAGGG)n sequence as a putative telomere motif in the plant family Chrysobalanaceae. This was bioinformatically confirmed by analysing template regions of identified telomerase RNAs.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nucleic Acids Research
ISSN
0305-1048
e-ISSN
1362-4962
Volume of the periodical
52
Issue of the periodical within the volume
D1
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
"D311"-"D321"
UT code for WoS article
001051997800001
EID of the result in the Scopus database
2-s2.0-85177656943