Simulation-based design of a microfabricated pneumatic electrospray nebulizer

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F15%3A00434464" target="_blank" >RIV/68081715:_____/15:00434464 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14740/15:00080741

Result on the web

<a href="http://dx.doi.org/10.1002/elps.201400387" target="_blank" >http://dx.doi.org/10.1002/elps.201400387</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/elps.201400387" target="_blank" >10.1002/elps.201400387</a>

Result language

angličtina

Original language name

Simulation-based design of a microfabricated pneumatic electrospray nebulizer

Original language description

A microfabricated pneumatic electrospray nebulizer has been developed and evaluated using computer simulations and experimental measurements of the mass spectrometry signals. The microdevice under development is designed for electrospray mass spectrometry interfacing without the need to fabricate an electrospray needle and can be used as a disposable or an integral part of a reusable system. The design of the chip layout was supported by computational fluid dynamics simulations. The tested microdeviceswere fabricated in glass using conventional photolithography, followed by wet chemical etching and thermal bonding. The performance of the microfabricated nebulizer was evaluated by means of time-of-flight mass spectrometry with a peptide mixture. It wasdemonstrated that the nebulizer, operating at supersonic speed of the nebulizing gas, produced very stable nanospray (900 nl/min) as documented by less than 0.1 % (standard error) fluctuation in total mass spectrometric signal intensity.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Electrophoresis

ISSN

0173-0835

e-ISSN

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Volume of the periodical

36

Issue of the periodical within the volume

3

Country of publishing house

DE - GERMANY

Number of pages

7

Pages from-to

386-392

UT code for WoS article

000349220500003

EID of the result in the Scopus database

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