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Comparative evaluation of protein composition in human breast cancer cells using mass spectrometry

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F16%3A00467709" target="_blank" >RIV/68081715:_____/16:00467709 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Comparative evaluation of protein composition in human breast cancer cells using mass spectrometry

  • Original language description

    Bottom-up proteomic approach was used for detailed characterization of proteins fromntwo human tumour cell lines representing major clinically different types of breastncancer. The aim was to show the differences between them on proteomic level. Herenwe present almost 100 unequivocally identified proteins out of which 60 were mutuallyndifferently expressed for MDA-MB-231 and MCF-7. Some well-known breast cancernmarkers like annexins A1, A2 and vimentin were found in the MDA-MB-231 cell line.nOn the other hand, MCF-7 cells were found to be positive for cytokeratins and keratinsnand thus we were able to distinguish both cell lines sufficiently.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CB - Analytical chemistry, separation

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    CECE 2016. 13th International Interdisciplinary Meeting on Bioanalysis

  • ISBN

    978-80-904959-4-4

  • ISSN

  • e-ISSN

  • Number of pages

    5

  • Pages from-to

    114-117

  • Publisher name

    Ústav analytické chemie AV ČR, v. v. i.

  • Place of publication

    Brno

  • Event location

    Brno

  • Event date

    Oct 17, 2016

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article