Subtractive manufacturing of customized hydroxyapatite scaffolds for bone regeneration

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081723%3A_____%2F17%3A00480609" target="_blank" >RIV/68081723:_____/17:00480609 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26620/17:PU124301
Result on the web
<a href="http://dx.doi.org/10.1016/j.ceramint.2017.05.177" target="_blank" >http://dx.doi.org/10.1016/j.ceramint.2017.05.177</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ceramint.2017.05.177" target="_blank" >10.1016/j.ceramint.2017.05.177</a>

Result language
angličtina
Original language name
Subtractive manufacturing of customized hydroxyapatite scaffolds for bone regeneration
Original language description
An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613 gm, which were connected through windows with an average diameter of 161 mu m. The compressive strength of the sintered foam reached an average value of 2 MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100 degrees C. The milling process was demonstrated and scaffold examples were successfully manufactured.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20504 - Ceramics

Project
<a href="/en/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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