Epoxy-based gelcasting of machinable hydroxyapatite foams for medical applications

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081723%3A_____%2F18%3A00491306" target="_blank" >RIV/68081723:_____/18:00491306 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26620/18:PU128107
Result on the web
<a href="http://dx.doi.org/10.1111/jace.15523" target="_blank" >http://dx.doi.org/10.1111/jace.15523</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/jace.15523" target="_blank" >10.1111/jace.15523</a>

Result language
angličtina
Original language name
Epoxy-based gelcasting of machinable hydroxyapatite foams for medical applications
Original language description
Machinable hydroxyapatite foams for subtractive manufacturing of customized bone scaffolds have been developed. The foams were prepared by direct foaming of water-based hydroxyapatite suspension with dissolved epoxy resin. The foams were consolidated by gelation of the epoxy-based suspension in air atmosphere. The effect of processing conditions on the foam structure was investigated. The foams had a cellular-like structure with interconnected pores. The sintered foam with 78% open porosity, the most frequent pore size 430m, and the most frequent interconnecting pore window size 150m, has been chosen as the foam with the optimal structure from the viewpoint of an application in bone regeneration. The compressive strength of this sintered foam reached 3.3MPa. The machinability of the optimal foam was investigated using computer numerical controlled (CNC) milling of a test pattern. The milling tests were carried out with the foam at different processing stages and after impregnation with paraffin wax. The best milling result was obtained for a dried foam impregnated with paraffin. The applicability of the whole processing chain was demonstrated and a customized scaffold was manufactured.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
20504 - Ceramics

Project
<a href="/en/project/NV17-31276A" target="_blank" >NV17-31276A: Comprehensive pre-clinical evaluation of lateral lumbar spine fusion with hybrid biodegradable nanocomposite porous implant.</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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