Excitation Specificity of Repolarization Parameters

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F11%3A00368135" target="_blank" >RIV/68081731:_____/11:00368135 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Excitation Specificity of Repolarization Parameters
Original language description
The excitation specificity of QT dynamic parameters was tested on three groups of subjects: healthy subjects; non-medicated hypertensive subjects with metabolic syndrome; and subjects with essential hypertension. Four different excitations of RR were used: bicycling exercise; tilt with breathing 0.1 and 0.33 Hz; and deep breathing. Linear dynamic feedback model of QT/RR coupling was supposed at the analysis and next repolarization parameters were tested: QTc; gain of QT/RR coupling for slow and fast RRvariability; time constant of QT adaptation; and random QT variability. Results: Dynamic repolarization parameters statistically significantly depend on the type of RR excitation. The gain of QT/RR coupling for slow RR variability, the time constant of QT adaptation and QTc are maximal at RR excitation given by the bicycling exercise. The frequency of breathing, i.e. corresponding vagal modulation has no effect on repolarization parameters.
Czech name
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Czech description
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Project
<a href="/en/project/ME09050" target="_blank" >ME09050: The analysis of dynamic and static properties of QT intervals</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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