Measure of the QT-RR Dynamic Coupling in Patients with the Long QT Syndrome
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F12%3A00385229" target="_blank" >RIV/68081731:_____/12:00385229 - isvavai.cz</a>
Alternative codes found
RIV/00159816:_____/12:#0000949
Result on the web
<a href="http://dx.doi.org/10.1111/j.1542-474X.2012.00526.x" target="_blank" >http://dx.doi.org/10.1111/j.1542-474X.2012.00526.x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1542-474X.2012.00526.x" target="_blank" >10.1111/j.1542-474X.2012.00526.x</a>
Alternative languages
Result language
angličtina
Original language name
Measure of the QT-RR Dynamic Coupling in Patients with the Long QT Syndrome
Original language description
The patients with the long QT syndrome type-1 (LQT-1) have an impaired adaptation of the QT interval to heart rate changes. Yet, the description of the dynamic QTRR coupling in genotyped LQT-1 has never been thoroughly investigated. Method: We propose amethod to model the dynamic QTRR coupling by defining a transfer function characterizing the relationship between a QT interval and its previous RR intervals measured from ambulatory Holter recordings. Three parameters are used to characterize the QTRR coupling: a fast gain (GainF), a slow gain (GainL), and a time constant (t). We investigated the values of these parameters across genders, and in genotyped LQT-1 patients with normal QTc interval duration (QTc < 470 ms). Results: The QTRR dynamic profiles are significantly different between LQT-1 patients (97) and controls (154): LQT-1 have longer QTc interval (453 +/- 35 vs. 384 +/- 26 ms, P < 0.0001), and an increased dependency of the QT interval to previous RR changes revealed by a l
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Annals of Noninvasive Electrocardiology
ISSN
1082-720X
e-ISSN
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Volume of the periodical
17
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
323-330
UT code for WoS article
000310248100004
EID of the result in the Scopus database
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