Oscillatory reactivity to effortful cognitive processing in the subthalamic nucleus and internal pallidum: a depth electrode EEG study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F17%3A00480383" target="_blank" >RIV/68081731:_____/17:00480383 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14740/17:00094885 RIV/00159816:_____/17:00068401

Result on the web

<a href="http://dx.doi.org/10.1007/s00702-017-1719-6" target="_blank" >http://dx.doi.org/10.1007/s00702-017-1719-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00702-017-1719-6" target="_blank" >10.1007/s00702-017-1719-6</a>

Result language

angličtina

Original language name

Oscillatory reactivity to effortful cognitive processing in the subthalamic nucleus and internal pallidum: a depth electrode EEG study

Original language description

This study investigates how complex motor-cognitive activities are processed in the subthalamic nucleus (STN) and internal globus pallidum (GPi), as adverse neuropsychiatric effects may accompany deep brain stimulation (DBS), mainly in Parkinson's disease (PD) and STN-DBS. Dystonia patients with GPi-DBS electrodes (n = 5) and PD subjects (n = 5) with STN-DBS electrodes performed two tasks: (1) copying letters, and (2) writing any letter other than that appearing on the monitor. The cognitive load of the second task was greater than that of the first. Intracranial local field potentials (LFPs) were analysed. A beta power decrease was the main correlate of the enhanced cognitive load during the second task in both structures, with a lateralization to the left side, mainly in the GPi. A gamma power increase linked with the increased cognitive activity was observed only in the STN. Differences were also observed in the theta and alpha bandpasses. Beta ERD reactivity seems to be essential during the processing of complex motor-cognitive tasks, increases with enhanced cognitive effort, and was observed in both the STN and GPi. Oscillatory reactivity to effortful cognitive processing in other frequency bands was less consistent, with differences between the studied nuclei. Lateralization of activity related to cognitive factors was observed mainly in the GPi.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

20601 - Medical engineering

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Neural Transmission

ISSN

0300-9564

e-ISSN

—

Volume of the periodical

124

Issue of the periodical within the volume

7

Country of publishing house

AT - AUSTRIA

Number of pages

12

Pages from-to

841-852

UT code for WoS article

000403773300006

EID of the result in the Scopus database

2-s2.0-85017182950