Epicardial Isochrones from a New High-Frequency ECG Imaging Technique

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F18%3A00509020" target="_blank" >RIV/68081731:_____/18:00509020 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.22489/CinC.2018.088" target="_blank" >http://dx.doi.org/10.22489/CinC.2018.088</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.22489/CinC.2018.088" target="_blank" >10.22489/CinC.2018.088</a>

Result language
angličtina
Original language name
Epicardial Isochrones from a New High-Frequency ECG Imaging Technique
Original language description
The aim of this study is to compare epicardial isochrone maps (EIM) derived from electrocardiographic (ECG) imaging with a new technique based on high frequency ECG isochrone maps (HFEIM) computation. nWe analyzed three subjects - normal, left bundle branch block (LBBB) and right bundle branch block (RBBB). Body surface potentials were measured: 5-minute supine, 2KHz sampling, 184 electrodes. These potentials were used for inverse reconstruction of EIM using patient-specific torsoheart geometry (CT). HFEIM was determined as follows: averaged body surface QRS amplitude envelopes 150-400 Hz (HFQRS) were projected onto the epicardium, the time delay from the onset of the QRS complex to centers of mass of projected HFQRS was computed. nThe EIM and HFEIM pattern of electrical activation was similar, especially for LBBB and RBBB subjects. The correlation between EIM and HFEIM activation times was 0.42, 0.82 and 0.83 for the NORMAL, LBBB and RBBB subjects respectively. Maximal dyssynchrony was about 40 ms lower for HFEIM than for EIM. nEIM and HFEIM provide comparable distribution of electrical delays but different reference values. Lower HFEIM dyssynchrony may reflect the electrical activation in an entire ventricular wall segment and may better correlate with local electro-mechanical function.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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