Label-free CARS microscopy through a multimode fiber endoscope
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F19%3A00510088" target="_blank" >RIV/68081731:_____/19:00510088 - isvavai.cz</a>
Result on the web
<a href="https://www.osapublishing.org/oe/fulltext.cfm?uri=oe-27-21-30055&id=421966" target="_blank" >https://www.osapublishing.org/oe/fulltext.cfm?uri=oe-27-21-30055&id=421966</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1364/OE.27.030055" target="_blank" >10.1364/OE.27.030055</a>
Alternative languages
Result language
angličtina
Original language name
Label-free CARS microscopy through a multimode fiber endoscope
Original language description
Multimode fibres have recently been employed as high-resolution ultra-thin endoscopes, capable of imaging biological structures deep inside tissue in vivo. Here, we extend this technique to label-free non-linear microscopy with chemical contrast using coherent anti-Stokes Raman scattering (CARS) through a multimode fibre endoscope, which opens up new avenues for instant and in-situ diagnosis of potentially malignant tissue. We use a commercial 125 mu m diameter, 0.29 NA GRIN fibre, and wavefront shaping on an SLM is used to create foci that are scanned behind the fibre facet across the sample. The chemical selectivity is demonstrated by imaging 2 mu m polystyrene and 2.5 mu m PMMA beads with per pixel integration time as low as 1 ms for epi-detection.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10306 - Optics (including laser optics and quantum optics)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Optics Express
ISSN
1094-4087
e-ISSN
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Volume of the periodical
27
Issue of the periodical within the volume
21
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
30055-30066
UT code for WoS article
000489954500053
EID of the result in the Scopus database
2-s2.0-85073542251