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Suppression of the non-linear background in a multimode fibre CARS endoscope

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F22%3A00553554" target="_blank" >RIV/68081731:_____/22:00553554 - isvavai.cz</a>

  • Result on the web

    <a href="https://opg.optica.org/boe/fulltext.cfm?uri=boe-13-2-862&id=468619" target="_blank" >https://opg.optica.org/boe/fulltext.cfm?uri=boe-13-2-862&id=468619</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1364/BOE.450375" target="_blank" >10.1364/BOE.450375</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Suppression of the non-linear background in a multimode fibre CARS endoscope

  • Original language description

    Multimode fibres show great potential for use as miniature endoscopes for imaging deep in tissue with minimal damage. When used for coherent anti-Stokes Raman scattering (CARS) microscopy with femtosecond excitation sources, a high band-width probe is required to efficiently focus the broadband laser pulses at the sample plane. Although graded-index (GRIN) fibres have a large bandwidth, it is accompanied by a strong background signal from four-wave mixing and other non-linear processes occurring inside the fibre. We demonstrate that using a composite probe consisting of a GRIN fibre with a spliced on step-index fibre reduces the intensity of the non-linear background by more than one order of magnitude without significantly decreasing the focusing performance of the probe. Using this composite probe we acquire CARS images of biologically relevant tissue such as myelinated axons in the brain with good contrast.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10306 - Optics (including laser optics and quantum optics)

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomedical Optics Express

  • ISSN

    2156-7085

  • e-ISSN

  • Volume of the periodical

    13

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    13

  • Pages from-to

    862-874

  • UT code for WoS article

    000750935000001

  • EID of the result in the Scopus database

    2-s2.0-85123415709