Discongruence of Mhc and cytochrome b phylogeographical patterns in Myodes glareolus (Rodentia: Cricetidae)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081766%3A_____%2F12%3A00375120" target="_blank" >RIV/68081766:_____/12:00375120 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1111/j.1095-8312.2011.01799.x" target="_blank" >http://dx.doi.org/10.1111/j.1095-8312.2011.01799.x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1095-8312.2011.01799.x" target="_blank" >10.1111/j.1095-8312.2011.01799.x</a>
Alternative languages
Result language
angličtina
Original language name
Discongruence of Mhc and cytochrome b phylogeographical patterns in Myodes glareolus (Rodentia: Cricetidae)
Original language description
In the present study, a phylogeographical approach was developed to analyse the influence of selection and history on a major histocompatibility complex (Mhc) class II gene polymorphism in European bank vole (Myodes glareolus) populations. We focused onexon 2 of the Dqa gene because it is highly variable in a large array of species and appears to evolve under pathogen-mediated selection in several rodent species. Using single-strand conformation polymorphism analysis and sequencing techniques, 17 Dqa-exon2 alleles, belonging to at least two different copies of Dqa gene, were detected over the distribution range of M. glareolus. Evidence of selection was found using molecular and population analyses. At the molecular level, we detected 13 codons evolving under positive selection pressures, most of them corresponding to regions coding for putative antigen binding sites of the protein. At the European level, we compared patterns of population structure for the Dqa-exon2 and cytochrome b
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EG - Zoology
OECD FORD branch
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Result continuities
Project
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Continuities
R - Projekt Ramcoveho programu EK
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biological Journal of the Linnean Society
ISSN
0024-4066
e-ISSN
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Volume of the periodical
105
Issue of the periodical within the volume
4
Country of publishing house
GB - UNITED KINGDOM
Number of pages
19
Pages from-to
881-899
UT code for WoS article
000301114900013
EID of the result in the Scopus database
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